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Our "Grape Seed Plus" contains an all natural antioxidant formula with enzymes to support optimal health and vitality. This product contains: Grape Seed Extract (!ActiVin IH636) is one of the most powerful antioxidants found. With proven antioxidant and chemoprotective properties to help fight against free radicals and oxidative stress. Grape Seed Extract provides a highly concentrated source of oligomeric proanthocyanidins (OPC's) which are known to possess a broad spectrum of biological, antioxidant and cardioprotective properties. Independent analysis has shown that !ActiVin IH636 is distinctly different from other grape seed extracts, and actually contains greater amounts of OPC's than other leading brands. These extraordinary nutrients have been proven to be 50 times more potent than vitamin E and 20 times more potent than vitamin C as free radical scavengers. OPC's are 100% bioavailable in humans and can be found in the blood within 20 minutes. OPC's have a unique ability to cross the blood brain barrier providing direct protection to the brain and central nervous system. Grape Seed Extract has been used therapeutically in Europe for decades to improve circulation, allergies, improve joint flexibility, reduce inflammation, rheumatoid arthritis, asthma, hay-fever, to lower high cholesterol levels, eczema, bronchitis, rheumatism, ulcers, varicose veins, retinopathy, premenstrual syndrome, edema, and to revitalize collagen to name just a few.

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Polygonum cuspidatum (Protykin IH727) is an all-natural, high-potency standardized extract of 50% trans-resveratrol. University studies show that resveratrol is an antioxidant, cardioprotectant, and antimutagenic agent. For centuries, oriental cultures have used the root of Polygonum cuspidatum for treating dysentery, headache, amenorrhea, mastitis and external trauma, as well as inflammatory and allergic diseases, hyperlipidemia and arteriosclerosis. Polygonum cuspidatum has also been used in Chinese medicine to treat bacterial and viral infections, asthma, arthritis, hepatitis, inflammatory diseases, hypertension and cancer.

Ginkgo Biloba Extract (Gbe-24/6 TM) outweighs all other Ginkgo Biloba's. It has a minimum of 24% Ginkgo Flavone Glycosides, at least 6% terpene lactones, more than 0.8% Ginkgolide B, the potent inhibitor of platelet aggregation, and less than 1 PPM of Ginkgolic acid. These percentages are the best in the industry. Ginkgo Biloba is an herb with powerful antioxidant effects in the brain, retina, and cardiovascular system. Ginkgo Biloba Extract has been shown to enhance mental acuity and memory, increase circulation in the brain and to the extremities, potentially inhibit the oxidative events leading to the progression of Alzheimer's and pre-senile dementia, and facilitate the removal and suspension of plaque off of the arterial walls.

The "Bad Guys"

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Could we live to be 120? The answer according to scientists is yes! In order to live up to our biological potential we must first deal with eliminating toxic invaders that destroy our health. We are constantly bombarded with cellular-damaging substances, called free radicals, generated by our environment from air, water pollutants, and other substances. Sunlight, radiation, drugs, pesticides, chemicals, solvents, fried foods, alcohol and tobacco smoke are just a few more examples of free-radical generating substances. Free radicals are also produced as the natural byproducts of metabolism. Oxygen free radicals are not always the "bad guys"; they serve a purpose in the body by burning bacteria and refuse matter. When our body is overburdened with free radicals out of control, they create a condition in the body termed oxidative stress, which can seriously compromise the immune system and gives rise to disease and decay, which may threaten our lives.

The War Within

The body is made up of billions of molecules that contain the basic elements and building blocks to support life. Free radicals are oxygen molecules that have lost an electron. These molecules are highly reactive, unstable, and capable of destroying an enzyme, protein molecule, or a complete cell through oxidation by stealing electrons from other nearby molecules. This sets off a free radical chain reaction in otherwise healthy cell membranes and tissues in the body. Free radicals multiply geometrically. They rapidly go out of control leading to breakdown in the organs and other systems of the body including the brain and nervous system.

DNA contains the blueprint for all healthy cell production, function and renewal. Every second of our lives billions of free radicals are waging war in our bodies trying to destroy our cells and alter genetic material. Free radicals can interfere with DNA coding so severely that it may make mutated enzymes that cannot function and cells that cannot reproduce. This seriously compromises the immune system and gives rise to disease and decay, which may threaten our lives.

The "Good Guys"

Our bodies try to protect us from free radical damage by producing antioxidant enzymes that neutralize them. However, they are not capable of handling this function without trace mineral co-factors and antioxidants provided from our diets. Antioxidants are protective molecules also referred to as free radical scavengers. Superoxide dismutase, commonly called SOD, is an example of an antioxidant enzyme the body produces. SOD is the primary antioxidant enzyme found in every cell of our body. Antioxidants destroy free radicals by feeding them electrons that change their chemical structure. These new stabilized compounds actually enhance the oxidative process.

The most widely known protective antioxidant from food sources are beta carotene and vitamins A, C, and E. We protect our cars from rust by painting them; we seal in freshness in our food by using plastic bags. We can help prevent premature aging, disease and decay by supplementing our diets with antioxidants. Some antioxidants are protectors of other antioxidants, some increase the potential of others, and some can even regenerate other antioxidants. For example, our super here, OPC, increases vitamin C potential which can in turn regenerate vitamin E that has been sacrificed to free radicals.

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The Super Heroes:

"Great Grape" and "Fine Pine"

Scientific studies validate proanthocyanidin nutrients as the most powerful antioxidant free radical scavengers known to man, and perhaps one of the greatest discoveries in history! After decades of research, OPCs have been given official recognition and distinction as "vitamin P", and the real vascular permeability remedy. Additional, these extraordinary nutrients have been proven to be 50 times more potent than vitamin C as free radical scavengers. OPC is 100% bioavailable in humans, can be found in the blood with 20 minutes, and remains in the body for up to 72 hours. Unlike other antioxidants, OPC has a unique ability to cross the blood brain barrier providing direct protection to the brain and central nervous system.

Cofactor to Vitamin C

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OPC has been used therapeutically in Europe for decades to improve circulation and diabetic retinopathy, reduce edema and arrest varicose veins. OPCs strengthen capillaries, arteries and veins. Also, by reducing capillary fragility, OPCs help prevent bruising. The improvement of resistance and permeability of capillaries make it easier for cells to accept nutrients and eliminate wastes (which is the purpose of the circulatory system). The heart pumps our blood and the arteries and veins carry it, but it is the capillaries that deliver nutrients to our cells, exchanging them for waste products. OPCs neutralize both water and fat-soluble free radicals within the cell membrane, and inhibit the release of certain enzymes that damage capillary walls. The effects of OPC supplementation can be seen in a very short period of time. In one study, conducted by Professor Henri Choussat of the University of Bordeaux in France, 47 people, 37 to 85 years old, were given one 100 milligram OPC supplement. In 72 hours they were found to have increased capillary resistance by 140%.

Blood Vessels

The Heart Protector

OPC not only helps to return flexibility to the skin, but also joints, arteries and other tissues such as the heart. The vascular system regulates the blood flow and supply to all cells and organs, and OPCs are the best-known protectors in terms of short and long term effects. OPCs also inhibit histamine production, which reduces inflammation and helps the arteries to resist attack by mutagens that contribute to cardiovascular disease. The proper functioning of the heart and a complete unhindered blood flow are the most essential physiological functions of the body.

Heart Disease is the number one killer in western countries. French women and men have 50% less heart disease than Americans do. This is in spite of the fact that the French generally have a much higher fat diet than most Americans. The French are famous for wine and it is generally served at mealtime. French wine drinkers have a 30% to 40% lower risk of coronary heart disease than non-wine drinkers. Red wine contains OPC. In making red wine the whole grape is fermented, including the crushed seeds and skins. In making white wine only squeezed juice is used which contains very little OPC.


Cholesterol is an essential-component of cell membranes and facilitates the transport of fatty acids. However, excess cholesterol is a potential threat to health. Vitamin C and its cofactors are known to degrade cholesterol into bile salts and help to eliminate it. The degradation and elimination of harmful cholesterol is enhanced by OPC. Once again the synergistic relationship between vitamin C and OPC is verified.

Varicose Veins Varicose vein symptoms can include aching, itching, burning, and fatigue. Severe varicose veins can lead to heart attacks, strokes, thrombophlebitis, and pulmonary embolism. Dr. G. Feine-Haake conducted a clinical study in Hamburg, Germany, to see if OPC supplementation would benefit people with varicose veins. Participating in the study were 110 people with varicose veins (41 were also experiencing nightly leg cramps). The individuals were given 90 milligrams of OPC daily. There was significant improvement in 77%. Additionally, 93% of the 41 individuals with leg cramps experienced relief.


Test Tubes

Edema is a condition that allows fluid to leak out of the bloodstream into the body tissues. It is generally characterized by swelling of the affected areas. Edema can occur in healthy people after prolonged periods of sitting, and some women experience it before menstruation. Sports injuries generally result in edema, and it can occur after certain surgical operations. Some pathological conditions can also lead to edema. Research shows that taking an OPC dietary supplement can significantly relieve edema. In one clinical trial, scientists from the University of Florence studied the effects of leg edema on 40 individuals having an average age of 60 years. The subjects were divided into two groups. The control group received 300 mg of OPC for 60 days. All of the subjects experienced relief of at least some of the symptoms. After 30 days, swelling disappeared in 26% of those taking OPC. After 60 days, 63% of the participants were free of any swelling of the legs.

OPC the Vision Protector

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Diabetic retinopathy is a manifestation of diabetes that causes microbleeding of the eye capillaries and is a common cause of blindness in adults. OPC has been a licensed treatment for this malady in France for many years. It has proven to reduce microbleeding of the capillaries markedly and improve eyesight noticeably. OPC has also been used for the prevention of complications after cataract surgery in diabetics.

Healthy people not suffering from eye defects or eye disease were chosen for a 1998 study about the effects OPC might have for relieving night blindness. The participants consisted of two groups, motorists who drove at night and computer screen watchers. Their resistance to blinding was measured after four weeks. Ninety-eight out of the one hundred people who participated in the test showed improvement.

The remaining ingredients are a full spectrum digestive enzyme formulation to provide cellular energy and increase the bio-availability of the nutrients in our products. Contains 90 servings per bottle. Suggested 1 capsule with 8 to 12oz. of water first thing in morning and 1 capsule mid-afternoon with water. Listed below is what each serving/capsule contains.

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